Cyanine5 alkyne

• CAT Number: I025342
• CAS Number: 1223357-57-0
• Molecular Formula: C35H42ClN3O
• Molecular Weight: 556.19
• Purity: 98%
• Synonyms: Cyanine5 alkyne, Cyanine 5 alkyne
• Target: Oxidative Phosphorylation
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 3,3-dimethyl-1-(6-oxo-6-(prop-2-yn-1-ylamino)hexyl)-2-((1E,3E)-5-((E)-1,3,3-trimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium chloride
• InChI: InChI=1S/C35H41N3O.ClH/c1-7-25-36-33(39)24-12-9-17-26-38-30-21-16-14-19-28(30)35(4,5)32(38)23-11-8-10-22-31-34(2,3)27-18-13-15-20-29(27)37(31)6;/h1,8,10-11,13-16,18-23H,9,12,17,24-26H2,2-6H3;1H
• InChIKey: VOWXUNAERRNFLE-UHFFFAOYSA-N
• SMILES: CC(C1=CC=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(NCC#C)=O)C4=CC=CC=C4C3(C)C.[Cl-]

Cyanine5 alkyne (Cat No.: I025342) is a fluorescent dye derivative that combines the bright, far-red fluorescence properties of Cyanine5 (Cy5) with an alkyne functional group for bioorthogonal labeling. It is widely used in click chemistry, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), for covalent attachment to azide-labeled biomolecules such as proteins, nucleic acids, or lipids. With excitation/emission maxima around 650/670 nm, Cyanine5 alkyne enables sensitive detection in fluorescence imaging, flow cytometry, and molecular diagnostics, offering low background interference and compatibility with multiplexed fluorescent labeling.

Reference

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