Cyanine5 NHS ester chloride

• CAT Number: I014914
• CAS Number: 1032678-42-4
• Molecular Formula: C38H46ClN3O4
• Molecular Weight: 644.2
• Purity: ≥95%
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 8-[(2Z)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]octanoate;chloride
• InChI: InChI=1S/C38H46N3O4.ClH/c1-37(2)28-18-13-15-20-30(28)39(5)32(37)22-10-9-11-23-33-38(3,4)29-19-14-16-21-31(29)40(33)27-17-8-6-7-12-24-36(44)45-41-34(42)25-26-35(41)43;/h9-11,13-16,18-23H,6-8,12,17,24-27H2,1-5H3;1H/q+1;/p-1
• InChIKey: DOOTYHJFDNJMLS-UHFFFAOYSA-M
• SMILES: CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCCCCCCC(=O)ON5C(=O)CCC5=O)(C)C)C)C.[Cl-]

Cyanine5 NHS ester chloride (Cat.No:I014914) is a fluorescent dye commonly used in biological research and imaging applications. It is a reactive dye that can be easily coupled to primary amines of biomolecules, such as proteins and nucleic acids. The resulting conjugates emit a bright red fluorescence, enabling visualization and detection in various experimental settings.

Reference

[1]. Brugada-Vilà P, et al. Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses. Theranostics. 2020;10(6):2744-2758.