Cyclo(L-prolyl-L-leucyl)

• CAT Number: R054814
• CAS Number: 2873-36-1
• Molecular Formula: C11H18N2O2
• Molecular Weight: 210.277
• Purity: 95%
• Synonyms: (3S-trans)-Hexahydro-3-(2-methylpropyl)-pyrrolo[1,2-a]pyrazine-1,4-dione; 3-Isobutylhexahydropyrrolo [1,2-a] pyrazine-1,4-dione; Cyclo(L-Leu-L-Pro); Cyclo(L-Pro-D-Leu); Cyclo(L-Pro-L-Leu); Cyclo(L-leucyl-L-prolyl); Cyclo(L-prolyl-L-leucyl); Cyclo(Pro
• Target: Fungal
• Appearance: White solid
• Storage: Store at -20°C
• Analysis method: HPLC
• IUPAC Name: (3S,8aS)-3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
• InChI: InChI=1S/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)/t8-,9-/m0/s1
• InChIKey: SZJNCZMRZAUNQT-IUCAKERBSA-N
• SMILES: CC(C)CC1C(=O)N2CCCC2C(=O)N1

Cyclo(L-Phe-L-Pro) (maculosin 6) is an analogue of a family of diketopiperazine metabolites isolated from a strain of Alternaria
alternata as a host-specific phytotoxin for spotted knapweed. Cyclo(L-Phe-L-Pro) occurs in many species of bacteria,
actinomycetes and fungi. It was also isolated from a marine tunicate-derived Streptomyces strain in 2011. Cyclo(L-Leu-L-Pro)
displays herbicidal and antibiotic activity. Cyclo(L-Leu-L-Pro) is an important chemical and bioassay standard for dereplication
of crude microbial extracts and is a useful chemo-taxonomic marker for bacteria, actinomycetes and fungi.