For research use only. Not for therapeutic Use.
Cyclocumarol (Cat.No:I025385) is an anticoagulant similar to but less potent than warfarin. This product may cause hemorrhaging if used indiscriminately.
| Catalog Number | I025385 |
| CAS Number | 518-20-7 |
| Synonyms | Actosin, Anticoagulans 63, BL 5, Compound 63 link, Cumopyran, Cumopyrin, Cyclocoumarol, Cyclocumarol, Methanopyranorin, Pyranocoumarin, Pyranocumarin |
| Molecular Formula | C20H18O4 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| IUPAC Name | 2H,5H-Pyrano(3,2-c)(1)benzopyran-5-one, 3,4-dihydro-2-methoxy-2-methyl-4-phenyl- |
| InChI | 1S/C20H18O4/c1-20(22-2)12-15(13-8-4-3-5-9-13)17-18(24-20)14-10-6-7-11-16(14)23-19(17)21/h3-11,15H,12H2,1-2H3 |
| InChIKey | ZGFASEKBKWVCGP-UHFFFAOYSA-N |
| SMILES | c12c(c3c(cccc3)oc2=O)O[C@@](OC)(C)C[C@@H]1c1ccccc1 |
| Reference | 1: Rayar AM, Lagarde N, Martin F, Blanchard F, Liagre B, Ferroud C, Zagury JF, Montes M, Sylla-Iyarreta Veitía M. New selective cyclooxygenase-2 inhibitors from cyclocoumarol: Synthesis, characterization, biological evaluation and molecular modeling. Eur J Med Chem. 2018 Feb 25;146:577-587. doi: 10.1016/j.ejmech.2018.01.054. Epub 2018 Jan 31. PubMed PMID: 29407982. |
