For research use only. Not for therapeutic Use.
Cycloheximide(CAT: I004513) is a powerful inhibitor of eukaryotic protein synthesis, commonly used in research to block the translocation step of protein elongation on ribosomes. By halting protein production, Cycloheximide allows scientists to study various cellular processes, including gene expression, protein turnover, and signal transduction. It is particularly useful in experiments examining the regulation of protein stability and degradation. Despite its extensive application in molecular biology and biochemistry, Cycloheximide is highly toxic and not used in clinical treatments. Its cytotoxic properties require careful handling, and it is an essential tool in understanding the dynamics of protein synthesis and degradation in cells.
| Catalog Number | I004513 |
| CAS Number | 66-81-9 |
| Synonyms | 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione |
| Molecular Formula | C₁₅H₂₃NO₄ |
| Purity | ≥95% |
| Target | Apoptosis Inducers |
| Solubility | DMSO: ≥ 33 mg/mL |
| Storage | Store at 4°C |
| IC50 | 532.5 nM |
| InChI | InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1 |
| InChIKey | YPHMISFOHDHNIV-FSZOTQKASA-N |
| SMILES | CC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C |
