Cyclopenin

• CAT Number: I011887
• CAS Number: 20007-87-8
• Molecular Formula: C17H14N2O3
• Molecular Weight: 294.31
• Purity: ≥95%
• Synonyms: NSC 604989; NSC-604989; NSC604989; NSC 114538; NSC-114538; NSC114538; Cyclopenin,;(3S,3/’R)-4-methyl-3/’-phenylspiro[benzo[e][1,4]diazepine-3,2/’-oxirane]-2,5(1H,4H)-dione
• Target: Cholinesterase (ChE)
• Solubility: Soluble in DMSO
• Storage: Store at 0-8 °C
• InChI: InChI=1S/C17H14N2O3/c1-19-15(20)12-9-5-6-10-13(12)18-16(21)17(19)14(22-17)11-7-3-2-4-8-11/h2-10,14H,1H3,(H,18,21)/t14-,17+/m1/s1
• InChIKey: APLKWZASYUZSBL-PBHICJAKSA-N
• SMILES: O=C(C1=CC=CC=C1N2)N(C)[C@]3([C@@](O3)([H])C4=CC=CC=C4)C2=O

Cyclopenin, also known as NSC 114538 and NSC 604989, is an inhibitor of acetylcholinesterase (AChE; IC50 = 2.04 μM for human recombinant AChE).

Reference

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