Cyclopentenyl uracil

For research use only. Not for therapeutic Use.

  • CAT Number: I045077
  • CAS Number: 90597-20-9
  • Molecular Formula: C10H12N2O5
  • Molecular Weight: 240.21
  • Purity: ≥95%
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Cyclopentenyl uracil, a non-cytotoxic inhibitor of uridine kinase, effectively blocks the salvage of circulating uridine by host and tumor tissues in the intact mouse[1].


Catalog Number I045077
CAS Number 90597-20-9
Synonyms

1-[(1R,4R,5S)-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidine-2,4-dione

Molecular Formula C10H12N2O5
Purity ≥95%
InChI InChI=1S/C10H12N2O5/c13-4-5-3-6(9(16)8(5)15)12-2-1-7(14)11-10(12)17/h1-3,6,8-9,13,15-16H,4H2,(H,11,14,17)/t6-,8-,9+/m1/s1
InChIKey FCWVOJUKQSHZIV-VDAHYXPESA-N
SMILES C1=CN(C(=O)NC1=O)C2C=C(C(C2O)O)CO
Reference

[1]. Cysyk RL, et al. Cyclopentenyl uracil: an effective inhibitor of uridine salvage in vivo. Biochem Pharmacol. 1995;49(2):203-207.
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