For research use only. Not for therapeutic Use.
Cyclopentenyl uracil, a non-cytotoxic inhibitor of uridine kinase, effectively blocks the salvage of circulating uridine by host and tumor tissues in the intact mouse[1].
Catalog Number | I045077 |
CAS Number | 90597-20-9 |
Synonyms | 1-[(1R,4R,5S)-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidine-2,4-dione |
Molecular Formula | C10H12N2O5 |
Purity | ≥95% |
InChI | InChI=1S/C10H12N2O5/c13-4-5-3-6(9(16)8(5)15)12-2-1-7(14)11-10(12)17/h1-3,6,8-9,13,15-16H,4H2,(H,11,14,17)/t6-,8-,9+/m1/s1 |
InChIKey | FCWVOJUKQSHZIV-VDAHYXPESA-N |
SMILES | C1=CN(C(=O)NC1=O)C2C=C(C(C2O)O)CO |
Reference | [1]. Cysyk RL, et al. Cyclopentenyl uracil: an effective inhibitor of uridine salvage in vivo. Biochem Pharmacol. 1995;49(2):203-207. |