Cyclophosphamide monohydrate

• CAT Number: I006338
• CAS Number: 6055-19-2 (hydrate)
• Molecular Formula: C7H17Cl2N2O3P
• Molecular Weight: 279.10
• Purity: ≥95%
• Synonyms: Ciclofosfamida; Ciclofosfamide; Cyclophosphamide monohydrate.;2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate
• Target: Cell Cycle/DNA Damage
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• IUPAC Name: N,N-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}
• InChI: InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• InChIKey: PWOQRKCAHTVFLB-UHFFFAOYSA-N
• SMILES: C1CNP(=O)(OC1)N(CCCl)CCCl.O

Cyclophosphamide Monohydrate(CAT: I006338) is a widely used alkylating agent with significant applications in oncology and immunology research. It functions as a prodrug, metabolized in the liver to form active compounds that cross-link DNA, leading to cell cycle arrest and apoptosis. This mechanism makes it a cornerstone for studying cancer therapies, particularly in lymphomas, leukemias, and solid tumors. Additionally, its immunosuppressive properties support investigations into autoimmune diseases and transplant rejection. Cyclophosphamide Monohydrate is invaluable for exploring combination therapies, mechanisms of resistance, and the impact of alkylating agents on both malignant and immune cells.