Cyclo(Pro-Val)

• CAT Number: I041051
• CAS Number: 5654-87-5
• Molecular Formula: C10H16N2O2
• Molecular Weight: 196.25
• Purity: ≥95%
• Synonyms: 3-propan-2-yl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
• InChI: InChI=1S/C10H16N2O2/c1-6(2)8-10(14)12-5-3-4-7(12)9(13)11-8/h6-8H,3-5H2,1-2H3,(H,11,13)
• InChIKey: XLUAWXQORJEMBD-UHFFFAOYSA-N
• SMILES: CC(C)C1C(=O)N2CCCC2C(=O)N1

Cyclo(Pro-Val) can be isolated from Pseudomonas fluorescens GcM5-1A and has cytotoxicity[1].
Cyclo(Pro-Val) (10, 20, and 30 μg/ml, 48 h) results in 65%, 73%, and 80% lethality of suspension cells, respectively.

Reference

[1]. Guo Q, et al. Two Cyclic Dipeptides from Pseudomonas fluorescens GcM5-1A Carried by the Pine Wood Nematode and Their Toxicities to Japanese Black Pine Suspension Cells and Seedlings in vitro. J Nematol. 2007 Sep;39(3):243-7.
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