For research use only. Not for therapeutic Use.
Non-selective somatostatin (sst) receptor antagonist. Blocks the effects of sst on airway <span class=/’symbol/’>β</span>-adrenergic function, CRF-induced suppression of gastric empyting, modulation of ACh release and growth hormone, insulin and glucagon release. Reported to act as an sst receptor agonist in human neuroblastoma cell line SH-SY5Y.
| Catalog Number | P000231 |
| CAS Number | 84211-54-1 |
| Synonyms | Alternative Name: Cyclo-(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[BZL]) |
| Molecular Formula | C44H57N7O6 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble to 1 mg/ml in 20% ethanol / water |
| Storage | Store at -20C |
| IUPAC Name | (3S,6S,9R,12S)-6-(4-aminobutyl)-12-benzyl-9-(1H-indol-3-ylmethyl)-3-[(1R)-1-phenylmethoxyethyl]-1,4,7,10,13-pentazacycloicosane-2,5,8,11,14-pentone |
| InChI | InChI=1S/C44H57N7O6/c1-30(57-29-32-18-8-5-9-19-32)40-44(56)46-25-15-3-2-10-23-39(52)48-37(26-31-16-6-4-7-17-31)42(54)50-38(27-33-28-47-35-21-12-11-20-34(33)35)43(55)49-36(41(53)51-40)22-13-14-24-45/h4-9,11-12,16-21,28,30,36-38,40,47H,2-3,10,13-15,22-27,29,45H2,1H3,(H,46,56)(H,48,52)(H,49,55)(H,50,54)(H,51,53)/t30-,36+,37+,38-,40+/m1/s1 |
| InChIKey | YHVHQZYJGWGAKN-ZUWUZHNASA-N |
| SMILES | CC(C1C(=O)NCCCCCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)OCC5=CC=CC=C5 |
