For research use only. Not for therapeutic Use.
Cyclosporine(Cat No.:A001060) is a potent immunosuppressive drug widely used to prevent organ transplant rejection and treat autoimmune disorders. It inhibits calcineurin, blocking the activation of T-cells and the production of interleukin-2 (IL-2), a key cytokine in immune responses. Originally derived from the fungus Tolypocladium inflatum, cyclosporine revolutionized transplant medicine. It is also used in conditions like psoriasis, rheumatoid arthritis, and dry eye disease. Despite its efficacy, it requires careful monitoring due to potential nephrotoxicity and other systemic side effects.
| CAS Number | 79217-60-0 |
| Synonyms | NA |
| Molecular Formula | C62H111N11O12 |
| Purity | ≥95% |
| Target | Microorganisms |
| Storage | 3 years -20C powder |
| IUPAC Name | 30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone |
| InChI | 1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41?,42?,43?,44?,45?,46?,47?,49?,50?,51?,52-/m1/s1 |
| InChIKey | PMATZTZNYRCHOR-KMSBSJHKSA-N |
| SMILES | CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
