For research use only. Not for therapeutic Use.
CYP11A1-IN-1(CAT: I040778) is a selective inhibitor of cytochrome P450 family 11 subfamily A member 1 (CYP11A1), a key mitochondrial enzyme responsible for the conversion of cholesterol to pregnenolone—the first and rate-limiting step in steroid hormone biosynthesis. By blocking CYP11A1 activity, this compound effectively reduces the production of steroid hormones such as glucocorticoids, mineralocorticoids, and sex hormones. CYP11A1-IN-1 is a valuable research tool for studying endocrine regulation, steroidogenesis, and the role of steroid hormones in cancer, metabolic disorders, and inflammatory diseases. It also holds potential for therapeutic exploration in conditions linked to hormonal imbalance or steroid-driven pathologies.
| CAS Number | 2744168-51-0 |
| Synonyms | tert-butyl 6-[[6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-4-oxopyran-3-yl]oxymethyl]-2-azaspiro[3.3]heptane-2-carboxylate |
| Molecular Formula | C27H34N2O5 |
| Purity | ≥95% |
| IUPAC Name | tert-butyl 6-[[6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-4-oxopyran-3-yl]oxymethyl]-2-azaspiro[3.3]heptane-2-carboxylate |
| InChI | InChI=1S/C27H34N2O5/c1-26(2,3)34-25(31)29-17-27(18-29)11-19(12-27)15-33-24-16-32-22(10-23(24)30)14-28-9-8-20-6-4-5-7-21(20)13-28/h4-7,10,16,19H,8-9,11-15,17-18H2,1-3H3 |
| InChIKey | FYDVRTQEHDKFTK-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)N1CC2(C1)CC(C2)COC3=COC(=CC3=O)CN4CCC5=CC=CC=C5C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
