CYP19A1/CYP11B2-IN-1

For research use only. Not for therapeutic Use.

  • CAT Number: M032813
  • CAS Number: 183500-36-9
  • Molecular Formula: C12H11N3O
  • Molecular Weight: 213.24
  • Purity: ≥95%
Inquiry Now

CYP19A1/CYP11B2-IN-1 (Cat No.: M032813) is a dual inhibitor targeting both CYP19A1 (aromatase) and CYP11B2 (aldosterone synthase), enzymes involved in steroidogenesis. By inhibiting these enzymes, CYP19A1/CYP11B2-IN-1 reduces the production of estrogen and aldosterone, which are key hormones in various physiological processes. This dual inhibition is particularly promising for the treatment of hormone-dependent cancers, such as breast cancer, and conditions related to excessive aldosterone, like hypertension and heart failure. Its potential in endocrine therapy and disease modulation is under active investigation.


CAS Number 183500-36-9
Synonyms

4-[[5-(hydroxymethyl)imidazol-1-yl]methyl]benzonitrile

Molecular Formula C12H11N3O
Purity ≥95%
InChI InChI=1S/C12H11N3O/c13-5-10-1-3-11(4-2-10)7-15-9-14-6-12(15)8-16/h1-4,6,9,16H,7-8H2
InChIKey ACFSBQWDVYWNRT-UHFFFAOYSA-N
SMILES C1=CC(=CC=C1CN2C=NC=C2CO)C#N
Reference

[1]. Tinivella A, et al. Discovery of a Potent Dual Inhibitor of Aromatase and Aldosterone Synthase. ACS Pharmacology & Translational Science. 2023 Nov 23.

Request a Quote