Cytochalasin E

• CAT Number: R027630
• CAS Number: 36011-19-5
• Molecular Formula: C28H33NO7
• Molecular Weight: 495.57
• Purity: ≥95%
• Synonyms: (7S,13E,16S,18R,19E)-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22-trione; Cytochalasin E; NSC 175151;?[4S-(1E,4R*,6S*,7E,11aR*,14R*,14aR*,15R*,15aS*,16aR*,16bR*)]-3,13,14,14a,15,15a,16a,16b-Octahydro-6-
• Target: Autophagy
• Storage: -20°C
• IUPAC Name: (1S,5E,7R,9S,11E,13S,14S,16R,17S,18S,19S)-19-benzyl-7-hydroxy-7,9,16,17-tetramethyl-2,4,15-trioxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-5,11-diene-3,8,21-trione
• InChI: InChI=1S/C28H33NO7/c1-16-9-8-12-19-23-27(4,35-23)17(2)21-20(15-18-10-6-5-7-11-18)29-24(31)28(19,21)36-25(32)34-14-13-26(3,33)22(16)30/h5-8,10-14,16-17,19-21,23,33H,9,15H2,1-4H3,(H,29,31)/b12-8+,14-13+/t16-,17-,19-,20-,21-,23-,26+,27+,28+/m0/s1
• InChIKey: LAJXCUNOQSHRJO-ZYGJITOWSA-N
• SMILES: CC1CC=CC2C3C(O3)(C(C4C2(C(=O)NC4CC5=CC=CC=C5)OC(=O)OC=CC(C1=O)(C)O)C)C

Cytochalasin E (Cat No.: R027630) is a natural compound derived from the Cytochalasin family of metabolites. It acts as an inhibitor of actin polymerization, disrupting the dynamics of the actin cytoskeleton. By binding to actin filaments, Cytochalasin E prevents the formation of new actin filaments and impairs cellular processes like cell division, migration, and intracellular trafficking. Due to its effects on the cytoskeleton, it is studied for its potential in cancer research, cell biology, and understanding cellular mechanics in various diseases.