Cytosine-5,6-d2

• CAT Number: M137046
• CAS Number: 106391-24-6
• Molecular Formula: C4H5N3O
• Molecular Weight: 113.116
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 4-amino-5,6-dideuterio-1H-pyrimidin-2-one
• InChI: InChI=1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)/i1D,2D
• InChIKey: OPTASPLRGRRNAP-QDNHWIQGSA-N
• SMILES: [2H]C1=C(NC(=O)N=C1[2H])N

Cytosine-5,6-d2 is a deuterated nucleobase featuring two deuterium atoms at positions 5 and 6 on the cytosine ring. This isotopically labeled compound is essential for research in nucleic acid chemistry, DNA/RNA studies, and epigenetics. The deuterium labeling allows for precise analysis using NMR spectroscopy and mass spectrometry, enabling detailed investigation of cytosine’s role in biological processes, such as DNA methylation and mutation analysis. Cytosine-5,6-d2 is particularly useful in studies involving the synthesis of labeled nucleotides, oligonucleotides, and in understanding the dynamics of nucleic acid interactions, providing reliable and accurate data for advanced biochemical research.