For research use only. Not for therapeutic Use.
CZC-8004 is an aminopyrimidine that binds a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. It inhibits these kinases at low micromolar concentrations and can be immobilized to capture and purify these enzymes.
| Catalog Number | R008857 |
| CAS Number | 916603-07-1 |
| Synonyms | N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenyl-2,4-pyrimidinediamine; |
| Molecular Formula | C17H16FN5 |
| Purity | ≥95% |
| Target | Protein Tyrosine Kinase/RTK |
| Storage | -20°C |
| IUPAC Name | 2-N-[4-(aminomethyl)phenyl]-5-fluoro-4-N-phenylpyrimidine-2,4-diamine |
| InChI | InChI=1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23) |
| InChIKey | UKOHFWNBTUJMMN-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN |
