D-Desthiobiotin (Cat No.: I018950) is a biotin derivative with versatile applications in biochemical research. It is commonly utilized in affinity chromatography and protein chromatography techniques to isolate and purify proteins. Additionally, D-Desthiobiotin can serve as a labeling agent for proteins and cells, facilitating their detection and separation in various experimental setups. Its strong affinity for avidin or streptavidin makes it particularly useful in biotin-streptavidin-based assays. Researchers regularly employ D-Desthiobiotin to streamline protein and cell studies, taking advantage of its specific and high-affinity binding properties to avidin-containing molecules.
| Catalog Number | I018950 |
| CAS Number | 533-48-2 |
| Molecular Formula | C₁₀H₁₈N₂O₃ |
| Purity | ≥95% |
| Storage | 2-8°C |
| IUPAC Name | 6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acid |
| InChI | InChI=1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1 |
| InChIKey | AUTOLBMXDDTRRT-JGVFFNPUSA-N |
| SMILES | CC1C(NC(=O)N1)CCCCCC(=O)O |
| Reference | [1]. Röhlen DL, et al. Toward a Hybrid Biosensor System for Analysis of Organic and Volatile Fatty Acids in Fermentation Processes. Front Chem. 2018 Jul 17;6:284. |
