For research use only. Not for therapeutic Use.
D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site[1].
Catalog Number | I045565 |
CAS Number | 24404-90-8 |
Synonyms | (4S)-2-(6-methoxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid |
Molecular Formula | C12H10N2O3S2 |
Purity | ≥95% |
InChI | InChI=1S/C12H10N2O3S2/c1-17-6-2-3-7-9(4-6)19-11(13-7)10-14-8(5-18-10)12(15)16/h2-4,8H,5H2,1H3,(H,15,16)/t8-/m1/s1 |
InChIKey | ZTQKCGHSTKIWFW-MRVPVSSYSA-N |
SMILES | COC1=CC2=C(C=C1)N=C(S2)C3=NC(CS3)C(=O)O |
Reference | [1]. Giuseppe Meroni, et al. D-Luciferin, derivatives and analogues: synthesis and in vitro/in vivo luciferase-catalyzed bioluminescent activity. Volume 2009, Issue 1, Reviews and Accounts, pp. 265-288 |