D-Mannitol 1,2:5,6-bis-acetonide

• CAT Number: I002229
• CAS Number: 1707-77-3
• Molecular Formula: C12H22O6
• Molecular Weight: 262.3
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: -20°C

Diacetone-D-mannitol （Cat No.:I002229）is a polyhydroxy compound that serves as a representative compound in this class. It possesses characteristics that make it an attractive chiral selector, including sample preparation and affordability. Diacetone-D-mannitol demonstrates excellent separation capabilities for various chiral drugs in NACE (non-aqueous capillary electrophoresis). However, its application in real sample separation and analysis is limited due to the differing pharmacodynamics, pharmacokinetics, and toxicological properties of its two enantiomers. Typically, the (R)-enantiomer exhibits desired effects, while the (S)-enantiomer is often ineffective, very weak, or even toxic.