For research use only. Not for therapeutic Use.
D-Mannoheptulose is a major non-structural carbohydrate in avocado. D-mannoheptulose is a specific inhibitor of D-glucose phosphorylation. D-Mannoheptulose can block insulin release and utilization of carbohydrate in rat[1][2][3].
Catalog Number | R011778 |
CAS Number | 3615-44-9 |
Synonyms | (3S,4S,5R,6R)-1,3,4,5,6,7-hexahydroxyheptan-2-one |
Molecular Formula | C7H14O7 |
Purity | ≥95% |
InChI | InChI=1S/C7H14O7/c8-1-3(10)5(12)7(14)6(13)4(11)2-9/h3,5-10,12-14H,1-2H2/t3-,5-,6-,7+/m1/s1 |
InChIKey | HSNZZMHEPUFJNZ-QMTIVRBISA-N |
SMILES | C(C(C(C(C(C(=O)CO)O)O)O)O)O |
Reference | [1]. D-mannoheptulose and perseitol in ‘Hass’ avocado: Metabolism in seed and mesocarp tissue. South African Journal of Botany. 2012 Mar; 79:159-165. [2]. Courtois P, et al. D-mannoheptulose phosphorylation by hexokinase isoenzymes. Int J Mol Med. 2001 Apr;7(4):359-63. [3]. Frenkel G, et al. Metabolic effects of insulin blockade by D-mannoheptulose in the sand rat (Psammomys obesus) and the rat. Gen Comp Endocrinol. 1972 Oct;19(2):341-4. |