D-Mannose-13C6

For research use only. Not for therapeutic Use.

  • CAT Number: R041343
  • CAS Number: 287100-74-7
  • Molecular Formula: 13C6H12O6
  • Molecular Weight: 186.11
  • Purity: ≥95%
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D-Mannose-13C6 is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific proteins[2].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].


Catalog Number R041343
CAS Number 287100-74-7
Synonyms

(2S,3S,4R,5R)-2,3,4,5,6-pentahydroxy(1,2,3,4,5,6-13C6)hexanal

Molecular Formula 13C6H12O6
Purity ≥95%
InChI InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4-,5-,6-/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1
InChIKey GZCGUPFRVQAUEE-CRWJSTOYSA-N
SMILES C(C(C(C(C(C=O)O)O)O)O)O
Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
 [Content Brief]

[2]. Genovese C, et al. Effects of a new combination of plant extracts plus d-mannose for the management of uncomplicated recurrent urinary tract infections. J Chemother. 2018 Apr;30(2):107-114.
 [Content Brief]

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