D-MYO-INOSITOL 1,4,5-TRISPHOSPHATE HEXAPOTASSIUM SALT

• CAT Number: M008143
• CAS Number: 103476-24-0
• Molecular Formula: C6H12O15P3 • 3K
• Molecular Weight: 534.4
• Purity: ≥95%
• Synonyms: Ins(1,4,5)-P3 (potassium salt);1,4,5-IP3 (potassium salt)
• Storage: -20°C
• InChI: InChI=1S/C6H15O15P3.6K/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12;;;;;;/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18);;;;;;/q;6*+1/p-6/t1-,2+,3+,4-,5-,6-;;;;;;/m1....../s1
• InChIKey: MQMSEISCCNPXIL-FMCZHWOXSA-K
• SMILES: [C@H]1([C@@H]([C@H]([C@@H]([C@H]([C@@H]1OP(=O)([O-])[O-])O)OP(=O)([O-])[O-])OP(=O)([O-])[O-])O)O.[K+].[K+].[K+].[K+].[K+].[K+]

D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt (IP3) is a biologically active molecule derived from phosphatidylinositol 4,5-bisphosphate (PIP2) via the action of phospholipase C. It plays a crucial role as a second messenger in cellular signal transduction, particularly in the regulation of intracellular calcium levels. IP3 binds to receptors on the endoplasmic reticulum, triggering the release of calcium ions into the cytoplasm, which in turn activates various calcium-dependent cellular processes, such as muscle contraction, secretion, and metabolism. The hexapotassium salt form enhances its solubility, making it suitable for research applications in biochemistry and cell biology, where it is used to study signaling pathways.