For research use only. Not for therapeutic Use.
D-<wbr></wbr><em>myo</em>-<wbr></wbr>Inositol-<wbr></wbr>4-<wbr></wbr>phosphate (Ins(4)P<sub>1</sub>) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P<sub>3</sub>, is a second messenger produced in cells by phospholipase C (PLC)-<wbr></wbr>mediated hydrolysis of phosphatidylinositol-<wbr></wbr>4,5-<wbr></wbr>diphosphate. Binding of Ins(1,4,5)P<sub>3</sub> to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(4)P<sub>1</sub> can be formed by dephosphorylation of Ins(1,4)P<sub>2</sub> by inositol polyphosphate 1-<wbr></wbr>phosphatase or dephosphorylated to inositol by inositol monophosphatase.
| Catalog Number | M095925 |
| CAS Number | 142760-33-6 |
| Synonyms | Ins(4)P1 (ammonium salt);4-IP1 (ammonium salt) |
| Molecular Formula | C6H11O9P · NH4 |
| Purity | ≥95% |
| Storage | -20°C |
| InChIKey | REMBBOONLXQKLK-FULNNGFGSA-N |
