D-threo-Ritalinic Acid

• CAT Number: R050423
• CAS Number: 129389-67-9
• Molecular Formula: C13H17NO2
• Molecular Weight: 219.284
• Purity: ≥95%
• Synonyms: (αR,2R)-α-Phenyl-2-piperidineacetic Acid; d-Ritalinic Acid
• Storage: Store at -20°C
• IUPAC Name: (2R)-2-phenyl-2-[(2R)-piperidin-2-yl]acetic acid
• InChI: InChI=1S/C13H17NO2/c15-13(16)12(10-6-2-1-3-7-10)11-8-4-5-9-14-11/h1-3,6-7,11-12,14H,4-5,8-9H2,(H,15,16)/t11-,12-/m1/s1
• InChIKey: INGSNVSERUZOAK-VXGBXAGGSA-N
• SMILES: C1CCNC(C1)C(C2=CC=CC=C2)C(=O)O

D-threo-Ritalinic acid is a metabolite of methylphenidate (Ritalin), a medication used to treat attention deficit hyperactivity disorder (ADHD). It is formed in the body through the metabolism of methylphenidate. D-threo-Ritalinic acid is pharmacologically inactive and is excreted in urine. Research on this metabolite contributes to understanding the pharmacokinetics and metabolism of methylphenidate and aids in drug monitoring and detection. Studying its elimination kinetics helps optimize dosing regimens and assess treatment efficacy and safety.