For research use only. Not for therapeutic Use.
D159687 (CAT: I019143) is a selective inhibitor of phosphodiesterase 4D (PDE4D). PDE4D is an enzyme that plays a role in the breakdown of cyclic adenosine monophosphate (cAMP), a cellular signaling molecule. By inhibiting PDE4D, D159687 increases the levels of cAMP, leading to various downstream effects. As a selective PDE4D inhibitor, D159687 specifically targets this enzyme subtype, potentially offering therapeutic applications in conditions where modulating cAMP levels is desired, such as inflammation, neurological disorders, and respiratory diseases.
Catalog Number | I019143 |
CAS Number | 1155877-97-6 |
Molecular Formula | C₂₁H₁₉ClN₂O₂ |
Purity | ≥95% |
Target | Phosphodiesterase (PDE) |
Reference | [1]. Zhang C, et al. Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System. Sci Rep. 2017 Jan 5;7:40115. |