Dabsyl chloride

• CAT Number: R026545
• CAS Number: 56512-49-3
• Molecular Formula: C14H14ClN3O2S
• Molecular Weight: 323.80
• Purity: ≥95%
• Synonyms: 4-[[4-(dimethylamino)phenyl]diazenyl]benzenesulfonyl chloride
• InChI: InChI=1S/C14H14ClN3O2S/c1-18(2)13-7-3-11(4-8-13)16-17-12-5-9-14(10-6-12)21(15,19)20/h3-10H,1-2H3
• InChIKey: VTVWTPGLLAELLI-UHFFFAOYSA-N
• SMILES: CN(C)C1=CC=C(C=C1)N=NC2=CC=C(C=C2)S(=O)(=O)Cl

Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.
Dabsyl chloride can give rise to mono-Dabsyl and bis-Dabsyl derivatives in the presence of multiple amino groups. Furthermore with respect to OPA derivatization, Dabsyl chloride can react with primary and also with secondary amines[1].

Reference

[1]. Francioso A, et al. HPLC Determination of Bioactive Sulfur Compounds, Amino Acids and Biogenic Amines in Biological Specimens. Adv Exp Med Biol. 2017;975:535-549.
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