Dac51

• CAT Number: I037907
• CAS Number: 2243944-92-3
• Molecular Formula: C20H17Cl2F3N4O4
• Molecular Weight: 505.27
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: CC1=C(C(=N[NH]1)C)C2=CC(=C(NC3=CC=CC=C3C(=O)NO)C(=C2)Cl)Cl.OC(=O)C(F)(F)F

Dac51 is a potent FTO inhibitor with an IC50 of 0.4 μM for inhibiting FTO demethylation.

Reference

[1] Yi Liu, et al. Cell Metab. 2021 Jun 1;33(6):1221-1233.e11.