Daidzin

• CAT Number: I004052
• CAS Number: 552-66-9
• Molecular Formula: C21H20O9
• Molecular Weight: 416.40
• Purity: ≥95%
• Synonyms: Daidzoside; NPI 031D
• Target: ALDH-Ⅰ
• Solubility: DMSO: ≥ 34 mg/mL
• Storage: 3 years -20℃ powder
• IUPAC Name: 3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
• InChI: InChI=1S/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1
• InChIKey: KYQZWONCHDNPDP-QNDFHXLGSA-N
• SMILES: C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O

Daidzin（Cat No.:I004052）is a naturally occurring isoflavone glycoside found in plants like kudzu root (Pueraria lobata) and soybeans. Known for its potential in treating alcohol dependence, Daidzin works by inhibiting aldehyde dehydrogenase (ALDH-2), which helps reduce alcohol consumption and its rewarding effects. Additionally, Daidzin has antioxidant and anti-inflammatory properties, making it beneficial for cardiovascular and metabolic health. It is widely studied for its therapeutic potential in managing alcohol-related disorders, oxidative stress, and hormone-related conditions, offering a promising approach in nutraceuticals and phytotherapy research.

Reference

[1]. Xie CI, et al. Daidzin, an antioxidant isoflavonoid, decreases blood alcohol levels and shortens sleep time induced by ethanol intoxication. Alcohol Clin Exp Res. 1994 Dec;18(6):1443-7.
[2]. Keung WM, et al. Kudzu root: an ancient Chinese source of modern antidipsotropic agents. Phytochemistry. 1998 Feb;47(4):499-506.
[3]. Keung WM, et al. Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1675-9.