For research use only. Not for therapeutic Use.
DAMGO is a synthetic peptide and selective mu-opioid receptor agonist widely used in neuropharmacological research. It mimics the effects of endogenous opioids, aiding in the study of pain mechanisms, receptor interactions, and signal transduction pathways. This compound is essential for developing new analgesics and understanding opioid receptor function. Researchers rely on DAMGO for precise and reliable results in advanced neurobiological and pharmacological investigations, contributing significantly to innovations in pain management and opioid research.
| Catalog Number | R014089 |
| CAS Number | 78123-71-4 |
| Synonyms | 158: PN: US20030176421 PAGE: 54-55 Caimed Protein;?3: PN: WO2009046859 PAGE: 98 Claimed Protein?DAGO; DAGOL; DAMGE; DAMGO; DAMPGO; H-Tyr-D-Ala(Me)Phe-NH-CH2-OH?NIH 10891; RX 783006; Tyr-D-Ala-Gly-(methyl)Phe-Gly-ol; Tyr-D-Ala-Gly-MePhe-Gly-ol; Tyr-D- |
| Molecular Formula | C26H35N5O6 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble to 2 mg/ml in sterile water |
| Storage | Desiccate at -20C |
| IUPAC Name | (2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-methylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide |
| InChI | InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 |
| InChIKey | HPZJMUBDEAMBFI-WTNAPCKOSA-N |
| SMILES | CC(C(=O)NCC(=O)N(C)C(CC1=CC=CC=C1)C(=O)NCCO)NC(=O)C(CC2=CC=C(C=C2)O)N |
