Dapagliflozin C2 Epimer

• CAT Number: C000456
• CAS Number: 2133407-75-5
• Molecular Formula: C₂₁H₂₅ClO₆
• Molecular Weight: 408.87
• Purity: ≥95%
• Synonyms: (2S,3S,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: 4°C, Hygroscopic
• IUPAC Name: (2S,3S,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20+,21+/m1/s1
• InChIKey: JVHXJTBJCFBINQ-MJCUULBUSA-N
• SMILES: CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl

Dapagliflozin C2 Epimer（Cat No.:C000456）, is a chemical compound that represents a specific stereoisomer of dapagliflozin. Dapagliflozin is an oral medication used to treat type 2 diabetes by inhibiting glucose reabsorption in the kidneys, leading to increased glucose excretion in urine. The C2 epimer refers to a particular arrangement of atoms at the carbon-2 position in the molecule, which can affect its pharmacological properties and efficacy.

Reference

Majewski, A., et al.: Przemysl Chemiczny, 95, 1129 (2016); Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)