Dapagliflozin Keto Impurity

• CAT Number: C000610
• CAS Number: 2169998-23-4
• Molecular Formula: C₂₁H₂₃ClO₇
• Molecular Weight: 422.86
• Purity: ≥95%
• Synonyms: (2-Chloro-5-((3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-ethoxyphenyl)methanone
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Hygroscopic
• IUPAC Name: [2-chloro-5-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]-(4-ethoxyphenyl)methanone
• InChI: InChI=1S/C21H23ClO7/c1-2-28-13-6-3-11(4-7-13)17(24)14-9-12(5-8-15(14)22)21-20(27)19(26)18(25)16(10-23)29-21/h3-9,16,18-21,23,25-27H,2,10H2,1H3/t16-,18+,19+,20-,21+/m1/s1
• InChIKey: YPBPJGIQJRTYNA-RQSWOZRGSA-N
• SMILES: CCOC1=CC=C(C=C1)C(=O)C2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl

Dapagliflozin Keto Impurity（Cat No.:C000610）, is a chemical compound that likely serves as an impurity or related substance in the synthesis or production of dapagliflozin, a medication used to treat type 2 diabetes. Impurities can be generated during the manufacturing process or may result from the degradation of the active pharmaceutical ingredient (API) over time. Characterizing and controlling impurities are essential aspects of pharmaceutical quality control to ensure the safety and efficacy of the final drug product. In the context of pharmaceutical research and production, the identification and quantification of impurities like Dapagliflozin Keto Impurity are crucial for maintaining product quality and safety standards.

Reference

Kasichayanula, S., et al.: Diabetes, Obesity and Metabolism 13, 47 (2011);