Dapivirine HCl

For research use only. Not for therapeutic Use.

  • CAT Number: I025540
  • CAS Number: 244768-47-6
  • Molecular Formula: C20H20ClN5
  • Molecular Weight: 365.87
  • Purity: 98%
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Dapivirine HCl(Cat No.:I025540)is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment and prevention of HIV. It works by binding to the reverse transcriptase enzyme, which is essential for the replication of the HIV virus. Dapivirine HCl has been developed as part of a vaginal ring formulation, offering a long-acting method for HIV prevention in women. It provides an alternative to daily oral antiretroviral therapy, with the potential to reduce HIV transmission in high-risk populations. Clinical trials have demonstrated its safety and efficacy, making it a promising addition to HIV prevention strategies.


Catalog Number I025540
CAS Number 244768-47-6
Synonyms

Dapivirine HCl; Dapivirine hydrochloride

Molecular Formula C20H20ClN5
Purity 98%
Solubility To be determined
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile;hydrochloride
InChI InChI=1S/C20H19N5.ClH/c1-13-10-14(2)19(15(3)11-13)24-18-8-9-22-20(25-18)23-17-6-4-16(12-21)5-7-17;/h4-11H,1-3H3,(H2,22,23,24,25);1H
InChIKey RHIYZDNOTUMYCA-UHFFFAOYSA-N
SMILES CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C.Cl

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