DAPK-IN-2

• CAT Number: I041141
• CAS Number: 304000-05-3
• Molecular Formula: C17H14N2O4
• Molecular Weight: 310.30
• Purity: ≥95%
• Synonyms: (4Z)-2-(3,4-dimethoxyphenyl)-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one
• IUPAC Name: (4E)-2-(3,4-dimethoxyphenyl)-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one
• InChI: InChI=1S/C17H14N2O4/c1-21-14-6-5-12(9-15(14)22-2)16-19-13(17(20)23-16)8-11-4-3-7-18-10-11/h3-10H,1-2H3/b13-8+
• InChIKey: VQKPPWJEZADXST-MDWZMJQESA-N
• SMILES: COC1=C(C=C(C=C1)C2=N/C(=C/C3=CN=CC=C3)/C(=O)O2)OC

DAPK-IN-2（Cat No.:I041141）is a small molecule inhibitor targeting the death-associated protein kinase 1 (DAPK1), a serine/threonine kinase involved in regulating apoptosis, autophagy, and tumor suppression. DAPK1 is implicated in various cellular processes, including response to stress, cancer progression, and immune regulation. DAPK-IN-2 works by selectively inhibiting DAPK1 activity, potentially providing a therapeutic strategy to modulate apoptosis in cancer cells or to improve immune responses in autoimmune diseases. Ongoing research aims to explore its efficacy and safety in treating cancers and other diseases where DAPK1 plays a crucial role in disease progression.