Dapoxetine-d6 Hydrochloride

• CAT Number: R047643
• CAS Number: 1246814-76-5
• Molecular Formula: C21H24ClNO
• Molecular Weight: 347.92
• Purity: ≥95%
• Synonyms: (αS)-N,N-(Dimethyl-d6)-α-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine; LY-210448-d6
• Storage: -20°C
• IUPAC Name: (1S)-3-naphthalen-1-yloxy-1-phenyl-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride
• InChI: InChI=1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1/i1D3,2D3
• InChIKey: IHWDIQRWYNMKFM-RURDCJKXSA-N
• SMILES: [2H]C([2H])([2H])N([C@@H](CCOC1=CC=CC2=CC=CC=C21)C3=CC=CC=C3)C([2H])([2H])[2H].Cl

Dapoxetine-d6 Hydrochloride（Cat No.:R047643） is a deuterated form of dapoxetine hydrochloride, enhanced with six deuterium atoms, which improves its analytical detection and stability in pharmacokinetic studies using NMR spectroscopy and mass spectrometry. This compound is essential for investigating the metabolism and therapeutic monitoring of dapoxetine, a medication primarily used for treating premature ejaculation. The isotopic labeling aids in precise measurement and understanding of dapoxetine’s absorption, distribution, and elimination, facilitating the optimization of dosing strategies and enhancing treatment efficacy. Dapoxetine-d6 Hydrochloride is a key tool in advancing urological and psychiatric research.