Dapsone-D8

• CAT Number: R001827
• CAS Number: 557794-38-4
• Molecular Formula: C12H12N2O2S
• Molecular Weight: 256.35
• Purity: ≥95%
• Synonyms: 4,4’-Sulfonylbisbenzeneamine-D8; 4,4’-Sulfonylbis-benzen-2,3,5,6-d4-amine
• Storage: -20°C
• IUPAC Name: 4-(4-amino-2,3,5,6-tetradeuteriophenyl)sulfonyl-2,3,5,6-tetradeuterioaniline
• InChI: InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2/i1D,2D,3D,4D,5D,6D,7D,8D
• InChIKey: MQJKPEGWNLWLTK-PGRXLJNUSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1N)[2H])[2H])S(=O)(=O)C2=C(C(=C(C(=C2[2H])[2H])N)[2H])[2H])[2H]

Dapsone-D8 (Cat No.:R001827) is a deuterated form of dapsone, extensively used in clinical medicine for its antibacterial and anti-inflammatory properties, particularly in the treatment of leprosy and dermatitis herpetiformis. This compound, labeled with eight deuterium atoms, enhances the precision and accuracy of pharmacokinetic and metabolic studies by providing increased stability and reduced exchange rates in biological systems. Dapsone-D8 (Major) is instrumental in tracing the metabolic pathways and elucidating the mechanism of action of dapsone, facilitating the development of more effective therapeutic protocols and improving patient outcomes in clinical settings.