For research use only. Not for therapeutic Use.
Daptomycin(Cat No.:A000562)is a cyclic lipopeptide antibiotic used to treat serious bacterial infections, including complicated skin infections and bloodstream infections caused by Gram-positive organisms like Staphylococcus aureus and Enterococcus species. It works by binding to bacterial cell membranes and disrupting essential ion gradients, leading to rapid cell death. Unlike many antibiotics, daptomycin maintains efficacy against resistant strains, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Known for its potency and unique mechanism, daptomycin is valuable in managing multidrug-resistant infections in hospital settings, supporting effective patient outcomes in difficult-to-treat cases.
Catalog Number | A000562 |
CAS Number | 103060-53-3 |
Synonyms | DAPTOMYCIN; Cubicin; 103060-53-3; Cidecin |
Molecular Formula | C72H101N17O26 |
Purity | ≥95% |
Target | DNA Synthesis |
Solubility | >81.1mg/mL in DMSO |
Storage | -20°C |
Reference | 1: Kato H, Hagihara M, Murakami E, Suematsu H, Nishiyama N, Koizumi Y, Yamagishi 2: Kreutzberger MA, Pokorny A, Almeida PF. Daptomycin-Phosphatidylglycerol <br> 4: Higashi Y, Nakamura S, Tsuji Y, Ogami C, Matsumoto K, Kawago K, Tokui K, 5: Gómez Casanova N, Siller Ruiz M, Muñoz Bellido JL. Mechanisms of resistance to 6: Heidary M, Khosravi AD, Khoshnood S, Nasiri MJ, Soleimani S, Goudarzi M. 7: Taylor R, Beriashvili D, Taylor S, Palmer M. Daptomycin Pore Formation Is <br> 9: Bhardwaj P, Hans A, Ruikar K, Guan Z, Palmer KL. Reduced chlorhexidine and 10: Chanderraj R, Banerjee M, Rao K. High-Dose Daptomycin and Mortality: The Case |