For research use only. Not for therapeutic Use.
Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively (patent WO2018064119A1, compound 405)[1].
| Catalog Number | I025559 |
| CAS Number | 2221010-42-8 |
| Synonyms | N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2-fluorophenyl)-2-methyl-1,3-oxazole-5-carboxamide |
| Molecular Formula | C21H18FN3O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H18FN3O4/c1-12-24-17(14-9-5-6-10-15(14)22)19(29-12)21(28)25-16(18(26)20(23)27)11-13-7-3-2-4-8-13/h2-10,16H,11H2,1H3,(H2,23,27)(H,25,28) |
| InChIKey | XYQHCMDVGIJOTA-UHFFFAOYSA-N |
| SMILES | CC1=NC(=C(O1)C(=O)NC(CC2=CC=CC=C2)C(=O)C(=O)N)C3=CC=CC=C3F |
| Reference | [1]. Brad Owen BUCKMAN, et al. Calpain modulators and therapeutic uses thereof. WO2018064119A1. |
