For research use only. Not for therapeutic Use.
DB0614（Cat No.:I042901）is a chemical compound known as a potent inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). It is primarily investigated for its potential in the treatment of type 2 diabetes by regulating blood glucose levels. By inhibiting DPP-4, DB0614 enhances the activity of incretin hormones, which increase insulin release and decrease glucagon levels in response to meals. This mechanism helps to improve glucose control and can contribute to reducing the risk of diabetes-related complications. Ongoing research explores its efficacy and safety profile in clinical applications.
| CAS Number | 2769753-47-9 |
| Synonyms | N-[3-[2-[4-[4-[5-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxypentyl]piperazin-1-yl]anilino]thieno[3,2-d]pyrimidin-7-yl]phenyl]methanesulfonamide |
| Molecular Formula | C41H42N8O7S2 |
| Purity | ≥95% |
| IUPAC Name | N-[3-[2-[4-[4-[5-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxypentyl]piperazin-1-yl]anilino]thieno[3,2-d]pyrimidin-7-yl]phenyl]methanesulfonamide |
| InChI | InChI=1S/C41H42N8O7S2/c1-58(54,55)46-28-8-5-7-26(23-28)31-25-57-34-24-42-41(45-37(31)34)43-27-11-13-29(14-12-27)48-20-18-47(19-21-48)17-3-2-4-22-56-33-10-6-9-30-36(33)40(53)49(39(30)52)32-15-16-35(50)44-38(32)51/h5-14,23-25,32,46H,2-4,15-22H2,1H3,(H,42,43,45)(H,44,50,51) |
| InChIKey | GZRWNUKQJFXVTH-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)NC1=CC=CC(=C1)C2=CSC3=CN=C(N=C32)NC4=CC=C(C=C4)N5CCN(CC5)CCCCCOC6=CC=CC7=C6C(=O)N(C7=O)C8CCC(=O)NC8=O |
