DBCO-amine

• CAT Number: I016734
• CAS Number: 1255942-06-3
• Molecular Formula: C₁₈H₁₆N₂O
• Molecular Weight: 276.33
• Purity: ≥95%
• Target: ADC Linker
• Storage: -20°C
• IUPAC Name: 3-amino-1-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)propan-1-one
• InChI: InChI=1S/C18H16N2O/c19-12-11-18(21)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13,19H2
• InChIKey: OCCYFTDHSHTFER-UHFFFAOYSA-N
• SMILES: C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCN

DBCO-amine (Cat No.:I016734) is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Reference

[1]. Ermira Pazolli, et al. Splicing modulator antibody-drug conjugates and methods of use. WO2019232449A1.