DBCO-Maleimide

• CAT Number: I017225
• CAS Number: 1395786-30-7
• Molecular Formula: C₂₅H₂₁N₃O₄
• Molecular Weight: 427.45
• Purity: ≥95%
• Target: ADC Linker
• Storage: -20°C
• IUPAC Name: N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
• InChI: InChI=1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)
• InChIKey: NHFQNAGPXIVKND-UHFFFAOYSA-N
• SMILES: C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)CCN4C(=O)C=CC4=O

DBCO-Maleimide (Cat No.:I017225) is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). ADCs are composed of an antibody to which is attached an ADC cytotoxin through an ADC linker. If you need to, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Reference

[1]. Modified antibody and radioactive metal-labelled antibody. WO2019203191A1.