DBCO-PEG4-biotin

• CAT Number: I014313
• CAS Number: 1255942-07-4
• Molecular Formula: C39H51N5O8S
• Molecular Weight: 749.92
• Purity: ≥95%
• Synonyms: DBCO-PEG4-biotin;N-(3-((Z)-dibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl)-1-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)-3,6,9,12-tetraoxapentadecan-15-amide
• Solubility: Soluble in DMSO
• IUPAC Name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide
• InChI: InChI=1S/C39H51N5O8S/c45-35(12-6-5-11-34-38-32(28-53-34)42-39(48)43-38)41-18-20-50-22-24-52-26-25-51-23-21-49-19-16-36(46)40-17-15-37(47)44-27-31-9-2-1-7-29(31)13-14-30-8-3-4-10-33(30)44/h1-4,7-10,32,34,38H,5-6,11-12,15-28H2,(H,40,46)(H,41,45)(H2,42,43,48)/t32-,34-,38-/m0/s1
• InChIKey: LNHSQAOQVNHUGL-QRBHCBQLSA-N
• SMILES: O=C1N[C@@]2([H])CS[C@@H](CCCCC(NCCOCCOCCOCCOCCC(NCCC(N3CC4=C(C=CC=C4)C#CC5=C3C=CC=C5)=O)=O)=O)[C@@]2([H])N1

DBCO-PEG4-biotin(CAT: I014313) is a bifunctional molecule combining a dibenzocyclooctyne (DBCO) group and a biotin moiety linked via a four-unit polyethylene glycol (PEG) spacer. The DBCO group enables copper-free click chemistry for conjugation with azide-containing biomolecules, while the biotin moiety facilitates affinity-based detection, purification, and immobilization through avidin or streptavidin binding. The PEG4 spacer enhances solubility and reduces steric hindrance, ensuring efficient bioconjugation. DBCO-PEG4-biotin is widely used in chemical biology, proteomics, and drug development, providing a reliable tool for studying biomolecular interactions and creating advanced functionalized systems.