For research use only. Not for therapeutic Use.
DBET6 (Cat. No: I020016) is a BET degrading enzyme based on PROTAC ‘s strong, selective, and cell permeability, and can also induce c-MYC down-regulation and apoptosis. It is effective in most cancer cell lines, and dBET6 has a significant degradation effect in cells at concentrations below the nanomolar level.
| Catalog Number | I020016 |
| CAS Number | 1950634-92-0 |
| Molecular Formula | C₄₂H₄₅ClN₈O₇S |
| Purity | ≥95% |
| Reference | [1]. Winter GE, et al. BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment. Mol Cell. 2017 Jul 6;67(1):5-18.e19. |
