DC-BPi-03

• CAT Number: I042291
• CAS Number: 2758411-46-8
• Molecular Formula: C14H14N4O2S
• Molecular Weight: 302.35
• Purity: ≥95%
• Synonyms: 6-(1H-indol-5-yl)-N-methyl-2-methylsulfonylpyrimidin-4-amine
• InChI: InChI=1S/C14H14N4O2S/c1-15-13-8-12(17-14(18-13)21(2,19)20)9-3-4-11-10(7-9)5-6-16-11/h3-8,16H,1-2H3,(H,15,17,18)
• InChIKey: RTONKOFFKFVXAW-UHFFFAOYSA-N
• SMILES: CNC1=NC(=NC(=C1)C2=CC3=C(C=C2)NC=C3)S(=O)(=O)C

DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC50 of 698.3 nM and a Kd of 2.81 μM[1].

Reference

[1]. Tian Lu, et al. Discovery of High-Affinity Inhibitors of the BPTF Bromodomain. J Med Chem. 2021 Aug 26;64(16):12075-12088.
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