DC661

• CAT Number: I019494
• CAS Number: 1872387-43-3
• Molecular Formula: C₃₁H₃₉Cl₂N₅
• Molecular Weight: 552.58
• Purity: ≥95%
• Target: Apoptosis
• Storage: Store at -20°C
• IUPAC Name: N-(7-chloroquinolin-4-yl)-N'-[6-[(7-chloroquinolin-4-yl)amino]hexyl]-N'-methylhexane-1,6-diamine
• InChI: InChI=1S/C31H39Cl2N5/c1-38(20-8-4-2-6-16-34-28-14-18-36-30-22-24(32)10-12-26(28)30)21-9-5-3-7-17-35-29-15-19-37-31-23-25(33)11-13-27(29)31/h10-15,18-19,22-23H,2-9,16-17,20-21H2,1H3,(H,34,36)(H,35,37)
• InChIKey: VJKCWFZTSDXOBS-UHFFFAOYSA-N
• SMILES: CN(CCCCCCNC1=C2C=CC(=CC2=NC=C1)Cl)CCCCCCNC3=C4C=CC(=CC4=NC=C3)Cl

DC661 (Cat No.:I019494) is a potent palmitoyl protein thioesterase 1 (PPT1) inhibitor that inhibits autophagy and acts as an anti-lysosomal agent. Compared with hydroxychloroquine (HCQ), DC661 has obvious acid hydrolysis and autophagy inhibitory effects. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Reference

[1]. Rebecca VW, et al. PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer. ancer Discov. 2019 Feb;9(2):220-229.