dCeMM3

• CAT Number: I043871
• CAS Number: 311787-85-6
• Molecular Formula: C14H11ClN4OS
• Molecular Weight: 318.78
• Purity: ≥95%
• Synonyms: 2-(1H-benzimidazol-2-ylsulfanyl)-N-(5-chloropyridin-2-yl)acetamide
• InChI: InChI=1S/C14H11ClN4OS/c15-9-5-6-12(16-7-9)19-13(20)8-21-14-17-10-3-1-2-4-11(10)18-14/h1-7H,8H2,(H,17,18)(H,16,19,20)
• InChIKey: OOYJNUNOVRCHJZ-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)NC(=N2)SCC(=O)NC3=NC=C(C=C3)Cl

dCeMM3（Cat No.:I043871）is a selective inhibitor of cyclin-dependent kinase 8 (CDK8), an enzyme involved in regulating transcription and cell cycle progression. By targeting CDK8, dCeMM3 disrupts the transcriptional machinery that governs gene expression related to cell growth, differentiation, and survival. This compound holds promise in cancer therapy by inhibiting tumor cell proliferation and inducing apoptosis in cancer cells with aberrant transcriptional activity. Additionally, dCeMM3 may be explored for its potential applications in inflammatory diseases, offering a strategy to modulate immune responses and control abnormal cell cycle regulation.