DCQVA

For research use only. Not for therapeutic Use.

  • CAT Number: I025618
  • CAS Number: 24967-10-0
  • Molecular Formula: C18H27NO3
  • Molecular Weight: 305.42
  • Purity: 98%
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DCQVA (Cat No.:I025618) is a synthetic compound that has been explored for its potential biological activities, particularly as an anti-inflammatory and anticancer agent. The compound contains a quinolinone backbone and various functional groups, which contribute to its interaction with cellular targets. In preclinical studies, DCQVA has shown promise in inhibiting the proliferation of cancer cells and modulating inflammatory pathways. Its exact mechanism of action is still under investigation, but early data suggest it could serve as a lead compound for further research into novel therapeutic agents.


Catalog Number I025618
CAS Number 24967-10-0
Synonyms

DCQVA;

Molecular Formula C18H27NO3
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name (4R)-4-[(6aR,7R,9aS,9bS)-6a-methyl-3-oxo-2,4,6,7,8,9,9a,9b-octahydro-1H-cyclopenta[f]quinolin-7-yl]pentanoic acid
InChI InChI=1S/C18H27NO3/c1-11(3-8-17(21)22)13-5-6-14-12-4-7-16(20)19-15(12)9-10-18(13,14)2/h9,11-14H,3-8,10H2,1-2H3,(H,19,20)(H,21,22)/t11-,12+,13-,14+,18-/m1/s1
InChIKey YHBFMULEUYRINA-RRLOCTAFSA-N
SMILES C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC=C3[C@H]2CCC(=O)N3)C
Reference

1: Nishimaki-Mogami T, Suzuki K, Okochi E, Takahashi A. Bezafibrate and clofibric
acid are novel inhibitors of phosphatidylcholine synthesis via the methylation of
phosphatidylethanolamine. Biochim Biophys Acta. 1996 Nov 11;1304(1):11-20. PubMed
PMID: 8944746.
2: Hayashi Y, Toyoda K, Imazawa T, Sato H, Okamiya H, Kurokawa Y, Takahashi J,
Mogami-Nishimaki T, Hayakawa S. Peroxisome proliferation of hepatocytes in rats
by a microbial degradation product of cholic acid,
4-(decahydro-6-methyl-3-oxocyclopenta(f)quinoline-7-yl)valeric acid. Exp Toxicol
Pathol. 1994 Jul;46(2):127-32. PubMed PMID: 7987070.
3: Nishimaki-Mogami T, Takahashi A, Hayashi Y. Activation of a
peroxisome-proliferating catabolite of cholic acid to its CoA ester. Biochem J.
1993 Nov 15;296 ( Pt 1):265-70. PubMed PMID: 8250853; PubMed Central PMCID:
PMC1137683.
4: Nishimaki-Mogami T, Takahashi A, Toyoda K, Hayashi Y. Induction of peroxisomal
beta-oxidation by a microbial catabolite of cholic acid in rat liver and cultured
rat hepatocytes. Biochem J. 1993 Oct 1;295 ( Pt 1):217-20. PubMed PMID: 8216219;
PubMed Central PMCID: PMC1134841.

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