For research use only. Not for therapeutic Use.
DCZ5418 is an inhibitor of TRIP13. DCZ5418 has anti-multiple myeloma activity in vitro and in vivo[1].
| Catalog Number | I040162 |
| CAS Number | 2883709-99-5 |
| Synonyms | (3aR,4S,7R,7aS)-3a,7a-dimethyl-2-[4-(pyridin-4-ylmethyl)phenyl]-4,5,6,7-tetrahydro-4,7-epoxyisoindole-1,3-dione |
| Molecular Formula | C22H22N2O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H22N2O3/c1-21-17-7-8-18(27-17)22(21,2)20(26)24(19(21)25)16-5-3-14(4-6-16)13-15-9-11-23-12-10-15/h3-6,9-12,17-18H,7-8,13H2,1-2H3/t17-,18+,21+,22- |
| InChIKey | DZGUDPKHBIPNCC-MTIDIVMFSA-N |
| SMILES | CC12C3CCC(C1(C(=O)N(C2=O)C4=CC=C(C=C4)CC5=CC=NC=C5)C)O3 |
| Reference | [1]. Sanfeng Dong, et al. Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo. Bioorg Med Chem Lett. 2023. |
