DDD107498 succinate

• CAT Number: I019314
• CAS Number: 2444781-71-7
• Molecular Formula: C₃₁H₃₇FN₄O₆
• Molecular Weight: 580.65
• Purity: ≥95%
• Target: Parasite; CaMK
• Storage: 4°C, away from moisture and light
• IUPAC Name: butanedioic acid;6-fluoro-2-[4-(morpholin-4-ylmethyl)phenyl]-N-(2-pyrrolidin-1-ylethyl)quinoline-4-carboxamide
• InChI: InChI=1S/C27H31FN4O2.C4H6O4/c28-22-7-8-25-23(17-22)24(27(33)29-9-12-31-10-1-2-11-31)18-26(30-25)21-5-3-20(4-6-21)19-32-13-15-34-16-14-32;5-3(6)1-2-4(7)8/h3-8,17-18H,1-2,9-16,19H2,(H,29,33);1-2H2,(H,5,6)(H,7,8)
• InChIKey: OTKHBNSZSWWVRJ-UHFFFAOYSA-N
• SMILES: C1CCN(C1)CCNC(=O)C2=CC(=NC3=C2C=C(C=C3)F)C4=CC=C(C=C4)CN5CCOCC5.C(CC(=O)O)C(=O)O

DDD107498 succinate（Cat No.:I019314） is a potent antibacterial agent targeting DNA synthesis. It acts by inhibiting DNA gyrase and topoisomerase IV, crucial enzymes involved in bacterial DNA replication and transcription. DDD107498 demonstrates broad-spectrum activity against Gram-negative and Gram-positive bacteria, including drug-resistant strains. As a prodrug, it is converted to the active form, DDD498, upon hydrolysis. With its strong antibacterial efficacy, DDD107498 succinate holds promise as a potential treatment for various bacterial infections, including those caused by drug-resistant pathogens such as carbapenem-resistant Enterobacteriaceae (CRE).