For research use only. Not for therapeutic Use.
DDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1, compound 129, can be used for osteoarthritis research[1].
| Catalog Number | I045608 |
| CAS Number | 1573053-23-2 |
| Synonyms | 4-[4-[[[4-chloro-2-[2-(dimethylamino)ethoxy]-5-methylphenyl]carbamoylamino]methyl]-2-methylphenoxy]-N-methylpyridine-2-carboxamide |
| Molecular Formula | C27H32ClN5O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H32ClN5O4/c1-17-13-22(25(15-21(17)28)36-11-10-33(4)5)32-27(35)31-16-19-6-7-24(18(2)12-19)37-20-8-9-30-23(14-20)26(34)29-3/h6-9,12-15H,10-11,16H2,1-5H3,(H,29,34)(H2,31,32,35) |
| InChIKey | YKRARSYSXDHLJH-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C=C1Cl)OCCN(C)C)NC(=O)NCC2=CC(=C(C=C2)OC3=CC(=NC=C3)C(=O)NC)C |
| Reference | [1]. Margarita Wucherer-Plietker, et al. Inhibiteurs de ddr2 pour le traitement de l’arthrose. Patent WO2014032755A2. |
