Deamino-hydroxytamoxifen

• CAT Number: I025688
• CAS Number: 77207-49-9
• Molecular Formula: C24H24O2
• Molecular Weight: 44.45
• Purity: 98%
• Synonyms: Deamino-hydroxytamoxifen; Deamino hydroxytamoxifen; Tamoxifen metabolite Y; Tamoxifen-ol.
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: Ethanol, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-, (Z)-
• InChI: InChI=1S/C24H24O2/c1-2-23(19-9-5-3-6-10-19)24(20-11-7-4-8-12-20)21-13-15-22(16-14-21)26-18-17-25/h3-16,25H,2,17-18H2,1H3/b24-23-
• InChIKey: TWASUFZMILCYJY-VHXPQNKSSA-N
• SMILES: CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCO)C=C2)C3=CC=CC=C3

Tamoxifen is a medication that is used to prevent breast cancer patients.

Reference

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2: Langan-Fahey SM, Tormey DC, Jordan VC. Tamoxifen metabolites in patients on long-term adjuvant therapy for breast cancer. Eur J Cancer. 1990;26(8):883-8. PubMed PMID: 2145931.
3: Etienne MC, Milano G, Fischel JL, Frenay M, François E, Formento JL, Gioanni J, Namer M. Tamoxifen metabolism: pharmacokinetic and in vitro study. Br J Cancer. 1989 Jul;60(1):30-5. PubMed PMID: 2803912; PubMed Central PMCID: PMC2247345.
4: Milano G, Etienne MC, Frenay M, Khater R, Formento JL, Renee N, Moll JL, Francoual M, Berto M, Namer M. Optimised analysis of tamoxifen and its main metabolites in the plasma and cytosol of mammary tumours. Br J Cancer. 1987 May;55(5):509-12. PubMed PMID: 3606944; PubMed Central PMCID: PMC2001713.
5: Murphy C, Fotsis T, Pantzar P, Adlercreutz H, Martin F. Analysis of tamoxifen and its metabolites in human plasma by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM). J Steroid Biochem. 1987 May;26(5):547-55. PubMed PMID: 3586671.